Kalpna Gupta Selected Research

hemoglobin AA

5/2022	Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease.
1/2019	Sensitization of nociceptors by prostaglandin E2-glycerol contributes to hyperalgesia in mice with sickle cell disease.
1/2017	Functional MRI BOLD response in sickle mice with hyperalgesia.

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Kalpna Gupta Research Topics

Disease

37	Pain (Aches) 06/2022 - 08/2002
18	Sickle Cell Anemia (Hemoglobin S Disease) 01/2021 - 01/2012
15	Neoplasms (Cancer) 01/2022 - 08/2002
13	Hyperalgesia 05/2022 - 07/2010
11	Inflammation (Inflammations) 01/2021 - 08/2009
10	Chronic Pain 06/2022 - 12/2015
6	Breast Neoplasms (Breast Cancer) 01/2021 - 08/2002
5	Wounds and Injuries (Trauma) 01/2019 - 03/2005
4	Neurogenic Inflammation 01/2019 - 09/2013
4	Hypoxia (Hypoxemia) 11/2017 - 09/2013
3	Acute Pain 01/2021 - 01/2017
3	Reperfusion Injury 12/2017 - 11/2017
2	Ulcer 10/2018 - 03/2005
1	Hemophilia A (Haemophilia) 06/2022
1	Disease Susceptibility (Diathesis) 06/2022
1	Hemorrhage 06/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2022
1	Leukemia 01/2022
1	Cognitive Dysfunction 01/2021
1	Hemolysis 01/2021
1	Phobic Disorders (Phobia) 01/2021
1	Epilepsy (Aura) 01/2020
1	Neuralgia (Stump Neuralgia) 01/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2019
1	Nociceptive Pain 01/2019

Drug/Important Bio-Agent (IBA)

27	Opioid Analgesics (Opioids)IBA 05/2022 - 03/2005
14	Analgesics (Analgesic Drugs)IBA 05/2022 - 11/2009
14	Morphine (MS Contin)FDA LinkGeneric 01/2019 - 08/2002
6	Sickle HemoglobinIBA 05/2022 - 07/2010
5	CannabinoidsIBA 01/2020 - 11/2009
5	Opioid Receptors (Opioid Receptor)IBA 01/2017 - 12/2011
4	Pharmaceutical PreparationsIBA 01/2022 - 09/2016
4	Biomarkers (Surrogate Marker)IBA 12/2019 - 01/2017
3	EndocannabinoidsIBA 05/2022 - 09/2017
3	hemoglobin AAIBA 05/2022 - 01/2017
3	Heme (Haem)IBA 01/2021 - 10/2017
3	NeuropeptidesIBA 01/2020 - 01/2017
3	Oxygen (Dioxygen)IBA 12/2017 - 01/2017
3	Hemoglobins (Hemoglobin)IBA 01/2017 - 03/2012
3	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2017 - 12/2013
2	EnzymesIBA 05/2022 - 12/2011
2	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 05/2022 - 01/2019
2	ProstaglandinsIBA 05/2022 - 01/2019
2	Dinoprostone (PGE2)FDA Link 05/2022 - 01/2019
2	Toll-Like Receptor 4IBA 01/2021 - 07/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2019
2	Arachidonic Acid (Vitamin F)IBA 01/2019 - 10/2017
2	CytokinesIBA 01/2019 - 12/2011
2	Substance PIBA 01/2019 - 09/2013
2	p38 Mitogen-Activated Protein KinasesIBA 01/2019 - 07/2010
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 07/2010
2	Thromboplastin (Tissue Factor)IBA 11/2017 - 02/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2017 - 08/2009
2	Cytochrome P-450 CYP3AIBA 10/2017 - 05/2011
2	AcidsIBA 10/2017 - 05/2011
2	BiguanidesIBA 10/2017 - 10/2017
2	CytochromesIBA 10/2017 - 10/2017
2	RNA (Ribonucleic Acid)IBA 01/2017 - 09/2014
2	Hemoglobin AIBA 01/2017 - 07/2010
2	Phosphates (Orthophosphate)IBA 07/2015 - 03/2005
2	Fentanyl (Sublimaze)FDA LinkGeneric 07/2015 - 03/2005
2	Cannabinoid Receptor AgonistsIBA 02/2012 - 07/2010
2	3- (2- hydroxy- 4- (1,1- dimethylheptyl)phenyl)- 4- (3- hydroxypropyl)cyclohexanolIBA 02/2012 - 07/2010
2	Estrogen ReceptorsIBA 05/2011 - 03/2006
2	Hydromorphone (Dilaudid)FDA LinkGeneric 01/2007 - 03/2005
1	Blood Coagulation Factors (Coagulation Factor)IBA 06/2022
1	AntioxidantsIBA 06/2022
1	EstersIBA 05/2022
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 05/2022
1	JZL 184IBA 05/2022
1	PhytochemicalsIBA 01/2022
1	Serotonin (5 Hydroxytryptamine)IBA 01/2021
1	salubrinalIBA 01/2021
1	ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA 01/2021
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2021
1	Biological ProductsIBA 01/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021
1	EndorphinsIBA 01/2021
1	OrexinsIBA 01/2020
1	CannabidiolIBA 01/2020
1	Dimenhydrinate (DMH)FDA LinkGeneric 01/2020
1	P-SelectinIBA 01/2019
1	purinoceptor P2Y6IBA 01/2019
1	Flurbiprofen (Froben)FDA LinkGeneric 01/2019
1	netupitantIBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 01/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Pancreatic Elastase (Elastase)IBA 01/2019
1	UDPglucose-Hexose-1-Phosphate Uridylyltransferase (Galactose 1 P Uridyltransferase)IBA 01/2019
1	SB 203580IBA 01/2019
1	Interleukin-8 (Interleukin 8)IBA 01/2019

Therapy/Procedure

13	Therapeutics 01/2021 - 03/2006
4	Analgesia 01/2020 - 09/2016
3	Drug Therapy (Chemotherapy) 01/2022 - 01/2021
2	Electroacupuncture 01/2019 - 09/2016
1	Intravenous Injections 05/2022
1	Radiotherapy 01/2022
1	Traction 01/2020
1	Length of Stay 01/2019